Theraworx Protect U-Pak

To request clinical trial data or speak to someone about adding the U-Pak to your protocols, contact us.

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When it comes to healthcare-associated UTIs4:

  • UTIs make up approximately 40% of all nosocomial infections, most of which are catheter-associated urinary tract infections (CAUTIs).
  • More than 1 million CAUTIs occur in the U.S. per year.
  • As many as 40% of hospital gram-negative bacteremia per year begin as UTIs.

Furthermore, UTIs are a notable cause of death in females, older men, and infant boys. They can lead to pyelonephritis with sepsis, renal damage in young children, pre-term birth, and complications resulting from antimicrobial resistance.5

Gaps in the Current Standard of Care

It is difficult to find options that are consistently proven both safe and effective in managing UTIs. While antibiotics can be effective in treating and preventing UTIs, antibiotic resistance is a mounting concern.6,7

Vaginal estrogen creams have shown effectiveness in preventing UTIs in post-menopausal women.8 However, some carry risks, cause adverse reactions, and are contraindicated in certain patients.9 While there have been conflicting views on cranberry for UTIs, there is little to no clinical evidence that it prevents UTIs.10,11 In fact, experts are now urging clinicians to avoid promoting cranberry as a viable option.12

Close Gaps in Care, With the U-Pak

The U-Pak, which includes peer-reviewed and clinically shown Theraworx Protect, is indicated to promote daily urinary health in those suffering from recurring UTIs.

Theraworx Protect U-Pak

Tested and documented safe for mucosa (vaginal, gingival, intestinal, epi-airway), the U-Pak contains a bottle of Theraworx Protect foam and a package of Theraworx Protect wipes, giving patients everything they need to cleanse and protect for daily urinary health.

The U-Pak has a variety of in-facility and at-home urogenital uses, including:

  • Anal cleansing after fecal evacuation or bowel movements
  • Daily cleansing to support menopausal health
  • Catheter care each time bladder is emptied
  • Cleansing before and after sexual intercourse

The clinical compendium for Theraworx Protect has been published in the American Journal of Infection Control (June 2018, April 2015), The Journal of Patient Care (June 2018), Annals of Infectious Disease and Epidemiology (November 2016), The Journal of Emergency Nursing (December 2010), and Infection Control Today (June 2008).

Contact us to learn about how the U-Pak can manage risks and promote daily urinary health in those suffering from recurring UTIs. See product details and purchasing information here.


  1. Castillo-Pino E, Medina M. An introduction to the epidemiology and burden of urinary tract infections. Ther Adv Urol. 2019;11. Published May 2, 2019. Accessed December 10, 2019.
  2. Rowe TA, Juthani-Mehta M. Urinary tract infection in older adults. Aging health. 2013;9(5):10.2217/ahe.13.38. doi:10.2217/ahe.13.38.
  3. Al-Badr A, Al-Shaikh G. Recurrent urinary tract infections management in women: a review. Sultan Qaboos Univ Med J. 2013;13(3):359–367.
  4. American Urological Association website. Medical student curriculum: adult UTI. Accessed June 24, 2019.
  5. Flores-Mireles AL, Walker JN, Caparon M, et al. Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nat Rev Microbol. 2015;13(5):269-284. doi:10.1038/nrmicro3432.
  6. Fisher H, Oluboyede Y, Chadwick T, et al. Continuous low-dose antibiotic prophylaxis for adults with repeated urinary tract infections (AnTIC): a randomised, open-label trial. Lancet Infect Dis. 2018;18(9):957-968. doi:10.1016/s1473-3099(18)30279-2.
  7. Lancet T. Balancing treatment with resistance in UTIs. Lancet. 2018;391(10134):1966. doi:10.1016/s0140-6736(18)31077-8.
  8. Jhang JF, Kuo HC. Recent advances in recurrent urinary tract infection from pathogenesis and biomarkers to prevention. Ci Ji Yi Xue Za Zhi. 2017;29(3):131–137. doi:10.4103/tcmj.tcmj_53_17.
  9. RXList website (for Rx Professional). Premarin vaginal cream. Accessed June 24, 2019.
  10. Guay DR. Cranberry and urinary tract infections. Drugs. 2009;69(7):775-807. doi:10.2165/00003495-200969070-00002.
  11. Juthani-Mehta M, Van Ness PH, Bianco L, et al. Effect of cranberry capsules on bacteriuria plus pyuria among older women in nursing homes: a randomized clinical trial. JAMA. 2016;316(18):1879–1887. doi:10.1001/jama.2016.16141.
  12. Nicolle LE. Cranberry for prevention of urinary tract infection? Time to move on. JAMA. 2016;316(18):1873–1874. doi:10.1001/jama.2016.16140.